Our research

Chronic inflammatory diseases

Chronic inflammatory diseases

Chronic inflammation damages any part of the human body and is a cause of diverse diseases. RDCE currently focuses on creating a new concept by clarifying the pathophysiology of chronic inflammatory diseases by protein assay such as cytokines and chemokines. Inflammatory endotype could predict severe disease and support correct drug selection, monitoring, and treatment decision. Through collaboration with academia, institutions, and companies in Europe, we create unique clinical value of potential biomarkers and deliver the research seeds to the IVD products.

Disease area

  • Respiratory (Asthma, COPD, ILD)
  • Allergy (including Atopic dermatitis)
  • Kidney diseases
  • Neurodegenerative diseases (Alzheimer‘s disease, Multiple Sclerosis)
  • Thrombosis

We are interested in discovering new disease areas for the application.

Publications / Conference

  • Type 1 inflammatory endotype relates to low compliance, lung fibrosis, and severe complications in COVID-19.
    T Hasegawa et al., Cytokine 2021 Jun 7;155618. doi: 10.1016/j.cyto.2021.155618. Online ahead of print
  • Type 1 inflammatory endotype relates to low compliance, lung fibrosis, and severe complications in COVID-19.
    T Hasegawa et al., European Society of Respiratory (Sep 2021): Oral presentation
  • Determination of physiological cardiac myosin-binging protein levels (cMyc) in healthy populations.
    K Inoue , M Shiozaki , S Sasaki , Y Sasaki , H Tamura , K Fukuda , N Kubota , M Hiki , T Funamizu , M Sumiyoshi , T Minamino  European Society of Cardiology (2021)
Regenerative cell medicine

Regenerative cell medicine

Since 1968, Sysmex has provided IVD testing in the fields of health management, diagnosis, treatment, and prognosis, which require diagnostic systems of a high standard. Recently we start applying our technologies to the pharmaceutical manufacturing process in regenerative cell therapy. Sysmex has three leading measurement platforms and know-how in the gene, cell, and protein analysis. We believe that our platforms contribute to your quality control process by measuring biological components in your interest.

Technology

Main Sysmex technologies in our laboratory are Immunochemistry and Haematology. These IVD devices have the strong advantage of transforming your research into a diagnostic test.

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